This review focuses on the deamidation of asparagine in monoclonal antibodies, one of the well-known degradation pathways.The importance of close monitoring of deamidation from early developability assessment to in vivo studies is discussed consequentially.The application of chromatographic and electrophoretic Sodas instruments for the separation o
Chilaiditi syndrome is an occasional radiographic anomaly characterized by the interposition of Seat Roller the bowels between the liver and the diaphragm.The presence of Chilaiditi syndrome can cause serious problem on percutaneous endoscopic gastrostomy (PEG) procedure, because the anomalous position of the transverse colon can obstruct the proce
Protein degradation via ubiquitination is a major proteolytic mechanism in cells.Once a protein is destined for degradation, it is tagged by multiple ubiquitin molecules.The synthesised polyubiquitin chains can be recognised by the 26S proteosome where proteins are degraded.These chains form Toys through multiple ubiquitination cycles that are simi
Abstract.Martyrdom plays a fundamental role in shaping the identity and faith journey of Christians in Asia.This study aimed to obtain understanding the factors that shape Christian martyrdom in Asia, especially the role of political power, religious rivalry, and xenophobia.Using a historical-comparative method, this study analyzed cases of persecu
Increasing pressures on land resources requires increased land use efficiency.Over 900 million ha of sandy soils throughout the world are extensively used for agricultural crop production, most requiring nutrient inputs.Although use of humic substances together with inorganic fertilizer as soil amendments has been introduced, their synergistic effe